| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IGFALS |
| Specificity: |
This antibody reacts specifically with IGFALS |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IGFALS/ALS |
| Gene ID: |
3483 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ALS, IGFBPs serve as shuttle molecules for both IGF-I and IGF-II and confer a level of regulation to the IGF signaling system by influencing the bio-availability, In human circulation, an extracellular protein involved in receptor-ligand binding and cell adhesion, are a family of seven proteins that have co-evolved with the IGFs, concentration and distribution of IGFs in the extracellular environment, detected primarily in plasma, is involved in protein-protein interactions that result in the formation of protein complexes, or IGFBPs, the IGF-binging protein complex requires ALS (IGFBP acid-labile subunit), The Insulin-like growth factor binding proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ALS |
| Also known as: |
IGFALS Polyclonal Antibody |
| Other name: |
Anti-IGFALS Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IGFALS |
| Short name: |
Anti-IGFALS (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, acid labile subunit (polyclonal), antibody to-insulin-like growth factor binding protein |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ACLSD and ALS, BT, IGFALS and IDBG-9328 and ENSG00000099769 and 3483, Igfals and IDBG-149536 and ENSMUSG00000046070 and 16005, acid labile subunit, insulin-like growth factor binding, nuclei, this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005520 : insulin-like growth factor binding, this GO :0005520 : insulin-like growth factor binding, 24635 and IDBG-648693 and ENSBTAG00000033299 and 532494, insulin-like growth factor binding protein |
| Identity: |
5468 |
| Gene: |
IGFALS |
More about : IGFALS |
| Long gene name: |
insulin like growth factor binding protein acid labile subunit |
| Synonyms gene name: |
acid labile subunit , insulin-like growth factor binding protein |
| Locus: |
16p13, 3 |
| Discovery year: |
1997-11-28 |
| GenBank acession: |
M86826 |
| Entrez gene record: |
3483 |
| Pubmed identfication: |
1379671 16114275 |
| Havana BLAST/BLAT: |
OTTHUMG00000128638 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database |