| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Glycoprotein VI |
| Specificity: |
This antibody reacts specifically with Glycoprotein VI |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GPVI/Glycoprotein VI |
| Gene ID: |
51206 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GPVI is expressed in megakaryocytes and platelets, GPVI plays an important role in platelet procoagulant activity which may contribute to arterial and venous thrombus formation, Patients deficient in GPVI suffer from mild hemorrhagic diathesis and their platelets fail to aggregate in response to collagen, There are three isoforms, Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GPVI |
| Also known as: |
Glycoprotein VI Polyclonal Antibody |
| Other name: |
Anti-Glycoprotein VI Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Glycoprotein VI |
| Short name: |
Anti-Glycoprotein VI (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Glycoprotein VI (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14388 |
| Gene: |
GP6 |
More about : GP6 |
| Long gene name: |
glycoprotein VI platelet |
| Synonyms gene name: |
glycoprotein VI (platelet) |
| Synonyms name: |
platelet glycoprotein VI |
| Locus: |
19q13, 42 |
| Discovery year: |
2001-01-19 |
| GenBank acession: |
AB035073 |
| Entrez gene record: |
51206 |
| Pubmed identfication: |
11027634 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000159709 |
| Locus Specific Databases: |
LRG_560 |