| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
KCNIP3 |
| Specificity: |
This antibody reacts specifically with KCNIP3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CSEN/KCNIP3 |
| Gene ID: |
30818 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants encoding different isoforms have been described, Jul 2008], Members of this family are small calcium binding proteins containing EF-hand-like domains, The encoded protein also functions as a calcium-regulated transcriptional repressor, They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, [provided by RefSeq, and hence neuronal excitability, and interacts with presenilins, in response to changes in intracellular calcium, which belong to the recoverin branch of the EF-hand superfamily, This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DREAM KCHIP3 |
| Also known as: |
KCNIP3 Polyclonal Antibody |
| Other name: |
Anti-KCNIP3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
KCNIP3 |
| Short name: |
Anti-KCNIP3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, calsenilin (polyclonal), antibody to-Kv channel interacting protein 3 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0015459 and potassium channel regulator activity and molecular function this GO :0019233 and sensory perception of pain and biological process this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0032993 and protein-DNA complex and cellular component this GO :0034765 and regulation of ion transmembrane transport and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043679 and axon terminus and cellular component this GO :0044325 and ion channel binding and molecular function this GO :0048265 and response to pain and biological process this GO :0048266 and behavioral response to pain and biological process this GO :0048306 and calcium-dependent protein binding and molecular function this GO :0071805 and potassium ion transmembrane transport and biological process, KCNIP3 and IDBG-61167 and ENSG00000115041 and 30818, Kcnip3 and IDBG-260417 and ENSMUSG00000079056 and 56461, calcium-dependent protein binding, calsenilin, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003677 and DNA binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005244 and voltage-gated ion channel activity and molecular function this GO :0005267 and potassium channel activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003714 : transcription corepressor activity and also this GO :0005244 : voltage-gated ion channel activity and also this GO :0005267 : potassium channel activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044325 : ion channel binding and also this GO :0048306 : calcium-dependent protein binding, this GO :0003714 : transcription corepressor activity, this GO :0005244 : voltage-gated ion channel activity, this GO :0005267 : potassium channel activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008022 : protein C-terminus binding, this GO :0015459 : potassium channel regulator activity, this GO :0043565 : sequence-specific DNA binding, this GO :0044325 : ion channel binding, this GO :0048306 : calcium-dependent protein binding, Kv channel interacting protein 3 |
| Identity: |
15523 |
| Gene: |
KCNIP3 |
More about : KCNIP3 |
| Long gene name: |
potassium voltage-gated channel interacting protein 3 |
| Synonyms gene: |
CSEN |
| Synonyms gene name: |
EF hand transcription factor Kv channel interacting protein 3, calsenilin, calsenilin , presenilin-binding protein |
| Synonyms name: |
calsenilin |
| Locus: |
2q11, 1 |
| Discovery year: |
2001-05-24 |
| GenBank acession: |
AF199599 |
| Entrez gene record: |
30818 |
| Pubmed identfication: |
9771752 10078534 |
| RefSeq identity: |
NM_013434 |
| Classification: |
Potassium voltage-gated channel regulatory subunits EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130392 |