| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
JWA |
| Specificity: |
This antibody reacts specifically with JWA |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human JWA |
| Gene ID: |
10550 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Environmental stressors to K562 cells such as heat shock, JWA is involved in environmental stress-responsive pathways in K562 cells, This response to environmental stressors suggests similiarity of JWA to heat shock protein 70 (HSP70), a higher temperature than the ideal body temperature of the organism from which the cell line was derived, a major co-receptor for human immunodeficiency virus (HIV), an erythroleukemia cell line derived from patients with chronic myeloid leukemia, and oxidative stress, regulate and increase the expres-sion of JWA, the production of oxygen-centered free radicals, which is upregulated by heat stress and toxic chemicals, JWA is a four-transmembrane environmental responsive protein which binds to the CC chemokine recepor 5 (CCR5) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PRAF3 JWA GTRAP3-18 DERP11 HSPC127 Yip6b |
| Also known as: |
JWA Polyclonal Antibody |
| Other name: |
Anti-JWA Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
JWA |
| Short name: |
Anti-JWA (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-JWA (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
16937 |
| Gene: |
ARL6IP5 |
More about : ARL6IP5 |
| Long gene name: |
ADP ribosylation factor like GTPase 6 interacting protein 5 |
| Synonyms gene name: |
ADP-ribosylation factor-like 6 interacting protein 5 |
| Synonyms name: |
PRA1 domain family 3 |
| Locus: |
3p14, 1 |
| Discovery year: |
2004-09-01 |
| GenBank acession: |
AF070523 |
| Entrez gene record: |
10550 |
| Pubmed identfication: |
11242046 11042152 |
| RefSeq identity: |
NM_006407 |
| Classification: |
YIP family |
| Havana BLAST/BLAT: |
OTTHUMG00000158773 |