| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DYRK3 |
| Specificity: |
This antibody reacts specifically with DYRK3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DYRK3 |
| Gene ID: |
8444 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Dyrk family members, Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, Dyrk1B, Dyrk1C, Dyrk2, Dyrk3, Dyrk3 is strongly expressed in testis, Dyrk4A and Dyrk4B, Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases, The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus, and very weakly expressed in spleen and adrenal gland, are thought to be involved in diverse cellular functions, including Dyrk1A (originally Dyrk), only after the onset of spermatogenesis, respectively, which is itself regulated by tyrosine phosphorylation, which is required for neurogenesis, Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RED REDK hYAK3-2 |
| Also known as: |
DYRK3 Polyclonal Antibody |
| Other name: |
Anti-DYRK3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DYRK3 |
| Short name: |
Anti-DYRK3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DYRK3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3094 |
| Gene: |
DYRK3 |
More about : DYRK3 |
| Long gene name: |
dual specificity tyrosine phosphorylation regulated kinase 3 |
| Synonyms gene name: |
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| Synonyms name: |
regulatory erythroid kinase dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5 protein kinase Dyrk3 |
| Locus: |
1q32, 1 |
| Discovery year: |
1998-10-29 |
| GenBank acession: |
Y12735 |
| Entrez gene record: |
8444 |
| Pubmed identfication: |
9748265 |
| RefSeq identity: |
NM_003582 |
| Havana BLAST/BLAT: |
OTTHUMG00000036339 |