| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BPGM |
| Specificity: |
This antibody reacts specifically with BPGM |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BPGM |
| Gene ID: |
669 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A disease characterized by hemolytic anemia, BPGM catalyzes the conversion of 3-D-glyceroyl phosphate to 2, Citrullinemia and Shwachman-Diamond syndrome, Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Involvement in disease:Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) , Lissencephaly, Pendred syndrome, Specifically, The gene encoding BPGM maps to human chromosome 7, Williams-Beuren syndrome, a reaction that is essential for controlling the concentration of 2, cholelithiasis and cholecystitis, splenomegaly, which houses over 1, 000 genes and comprises nearly 5% of the human genome, 3-BPG within the cell, 3-BPG), 3-bisD-glycerate (2, 3-bisphosphoglycerate mutase) is a 259 amino acid protein that belongs to the phosphoglycerate mutase family and exists as a homodimer that plays a crucial role in the regulation of hemoglobin oxygen, BPGM (2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
BPGM Polyclonal Antibody |
| Other name: |
Anti-BPGM Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BPGM |
| Short name: |
Anti-BPGM (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-BPGM (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1093 |
| Gene: |
BPGM |
More about : BPGM |
| Long gene name: |
bisphosphoglycerate mutase |
| Synonyms gene name: |
2, 3-bisphosphoglycerate mutase |
| Locus: |
7q33 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
BC017050 |
| Entrez gene record: |
669 |
| RefSeq identity: |
NM_001724 |
| Classification: |
Bisphosphoglycerate phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000155380 |