| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GPBB |
| Specificity: |
This antibody reacts specifically with GPBB |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GPBB/PYGB |
| Gene ID: |
5834 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Because of its fundamental role in the metabolism of glycogen, Glycogen phosphorylase (also known as GP) is an allosteric enzyme important in carbohydrate metabolism, Glycogen phosphorylase catalyzes the phosphorylation of glycogen to Glc-1-P, Its activity is regulated through either noncovalent binding of metabolites or by covalent modification, PYGB, PYGL and PYGM, There are three genes which encode the brain, fructose kinase-2/fructose 2, glycogen phosphorylase has been a target for the design of inhibitory compounds, liver and muscle forms of glycogen phosphorylase, which could be valuable in the therapeutic treatment of type 2 diabetes mellitus, 6-bisphosphatase (PFK-2) stimulates the synthesis and degradation of fructose 2, 6-bisphosphate, Glycolysis is an evolutionarily conserved series of ten chemical reactions that utilizes eleven enzymes to concomitantly generate pyruvate and ATP from glucose |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Glycogen Phosphorylase Isoenzyme BB, Glycogen phosphorylase, Glycogen phosphorylase B, Glycogen phosphorylase brain form, MGC9213, PYGB, PYGB_HUMAN, Phosphorylase glycogen brain, brain form, Brain glycogen phosphorylase |
| Also known as: |
GPBB Polyclonal Antibody |
| Other name: |
Anti-GPBB Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GPBB |
| Short name: |
Anti-GPBB (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GPBB (polyclonal) |
| Alternative technique: |
polyclonals |