| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PSMA7/Proteasome 20S alpha 7 |
| Specificity: |
This antibody reacts specifically with PSMA7/Proteasome 20S alpha 7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 7 |
| Gene ID: |
5688 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions, Interacts with some important proteins involved in transcription factor regulation, Leu, Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation, Phe, Plays a role in hepatitis C virus internal ribosome entry site-mediated translation, Plays an important role in the regulation of cell proliferation or cell cycle control, Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response, The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions, The proteasome has an ATP-dependent proteolytic activity, Tyr, and Glu adjacent to the leaving group at neutral or slightly basic pH, and apoptosis, cell cycle transition, cell differentiation, immune and stress response, transcriptional regulation, viral replication and even tumor initiation and progression, The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
XAPC7 C6 HSPC RC6-1 |
| Also known as: |
PSMA7/Proteasome 20S alpha 7 Antibody |
| Other name: |
Anti-PSMA7/Proteasome 20S alpha 7 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PSMA7/Proteasome 20S alpha 7 |
| Short name: |
Fluor 594, Anti-PSMA7/Proteasome 20S alpha 7 |
| Label: |
ALEXA |
| Alternative name: |
7/protein degradation aggregate 20S a 7, ALEXA Fluor 594, a classification, macropain) subunit, antibody to-proteasome (prosome |
| Alternative to gene target: |
7, C6 and HSPC and RC6-1 and XAPC7, PSMA7 and IDBG-640990 and ENSBTAG00000005127 and 505050, PSMA7 and IDBG-83912 and ENSG00000101182 and 5688, Psma7 and IDBG-213730 and ENSMUSG00000027566 and 26444, TAP-dependent and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004298 and threonine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005839 and proteasome core complex and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, alpha type, alpha-subunit complex and cellular component this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, identical protein binding, macropain) subunit, nuclei, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0019773 and proteasome core complex, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004298 : threonine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0004298 : threonine-type endopeptidase activity, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, proteasome (prosome |
| Identity: |
9536 |
| Gene: |
PSMA7 |
More about : PSMA7 |
| Long gene name: |
proteasome subunit alpha 7 |
| Synonyms gene name: |
7 , alpha type, macropain) subunit, proteasome (prosome |
| Synonyms name: |
proteasome subunit XAPC7 proteasome subunit RC6-1 |
| Locus: |
20q13, 33 |
| Discovery year: |
1995-11-22 |
| GenBank acession: |
AF022815 |
| Entrez gene record: |
5688 |
| Pubmed identfication: |
8764072 |
| RefSeq identity: |
NM_002792 |
| Classification: |
Proteasome |
| Havana BLAST/BLAT: |
OTTHUMG00000032895 |