| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RanBP2 |
| Specificity: |
This antibody reacts specifically with RanBP2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RanBP2 |
| Gene ID: |
5903 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In humans, Ran BP-2 is a large scaffold cyclophilin-related protein expressed in photoreceptor cells, Ran BP-2 localization at cytoplasmic fibrils emanating from the nuclear pore complex and interaction with the Ran-GTPase support its role in nucleocytoplasmic transport processes, Ran-binding protein 2 (Ran BP-2 or Nup358), This genetic heterogeneity renders further significance of this genomic region in human disease due to its possible involvement in genetically linked disorders such as juvenile nephronophthisis, congenital hepatic fibrosis and chorioretinal dysplasia, contains four Ran-binding domains, the Ran BP-2 gene is partially duplicated in a gene cluster and lies in a hot spot for recombination on chromosome 2q, The nuclear pore complex protein |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NUP358 ADANE |
| Also known as: |
RanBP2 Polyclonal Antibody |
| Other name: |
Anti-RanBP2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RanBP2 |
| Short name: |
Anti-RanBP2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RanBP2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9848 |
| Gene: |
RANBP2 |
More about : RANBP2 |
| Long gene name: |
RAN binding protein 2 |
| Synonyms gene: |
ANE1 |
| Synonyms gene name: |
acute necrotizing encephalopathy 1 (autosomal dominant) |
| Synonyms name: |
nucleoporin 358 |
| Locus: |
2q13 |
| Discovery year: |
1996-11-14 |
| GenBank acession: |
D42063 |
| Entrez gene record: |
5903 |
| Pubmed identfication: |
7724562 19118815 |
| RefSeq identity: |
NM_006267 |
| Classification: |
Zinc fingers RANBP2-type Tetratricopeptide repeat domain containing Cyclophilin peptidylprolyl isomerases Nucleoporins |
| Havana BLAST/BLAT: |
OTTHUMG00000130981 |