| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RNF131 |
| Specificity: |
This antibody reacts specifically with RNF131 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PJA2/RNF131 |
| Gene ID: |
9867 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
E3 ubiquitin-protein ligase activity, Encoded by a gene that maps to human chromosome 5q21, PJA2 binds to a variety of E2s and interacts with ubiquitin-conjugating enzymes, PJA2 localizes to both endoplasmic reticulum and Golgi apparatus membranes, PJA2 shares 52% identity with PJA1, Participating in E2-dependent, RNF131 (ring finger protein 131) or Neurodap1, Significantly conserved in chimpanzee, also known as E3 ubiquitin-protein ligase praja-2, chicken and zebrafish, cow, dog, in vitro, is a 708 amino acid protein that contains one ring-type zinc finger and exists as two alternatively spliced isoforms, mouse, rat, such as UBE2D2, which is involved in protein ubiquitination in brain and may play a role in X-linked mental retardation, 3, PJA2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0438 Neurodap1 |
| Also known as: |
RNF131 Polyclonal Antibody |
| Other name: |
Anti-RNF131 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RNF131 |
| Short name: |
Anti-RNF131 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RNF131 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17481 |
| Gene: |
PJA2 |
More about : PJA2 |
| Long gene name: |
praja ring finger ubiquitin ligase 2 |
| Synonyms gene: |
RNF131 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , ring finger protein 131 praja ring finger 2 praja ring finger 2 |
| Locus: |
5q21, 3 |
| Discovery year: |
2003-05-21 |
| GenBank acession: |
AB007898 |
| Entrez gene record: |
9867 |
| RefSeq identity: |
NM_014819 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000128750 |