| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RNF130 |
| Specificity: |
This antibody reacts specifically with RNF130 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RNF130 |
| Gene ID: |
55819 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
G1RZFP (G1-related zinc finger protein) or GOLIATH, Implicated in the regulation of growth factor withdrawal-induced apoptosis of myeloid precursor cells, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF130 (ring finger protein 130), RNF130 contains one PA (protease associated) domain and a single RING-type zinc finger, RNF130 is encoded by a gene located on human chromosome 5q35, also known as GP, is a 419 amino acid single-pass type I membrane protein that shares similarity with a Drosophila zinc-finger protein found in mesoderm known as g1, 3, 3 and mouse chromosome 11 B1, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GP G1RZFP GOLIATH |
| Also known as: |
RNF130 Polyclonal Antibody |
| Other name: |
Anti-RNF130 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RNF130 |
| Short name: |
Anti-RNF130 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ring finger protein 130 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
RNF130 and IDBG-62047 and ENSG00000113269 and 55819, RNF130 and IDBG-640909 and ENSBTAG00000004856 and 525735, Rnf130 and IDBG-167981 and ENSMUSG00000020376 and 59044, metal ion binding, nuclei, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0012501 and programmed cell death and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0046872 and metal ion binding and molecular function, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0046872 : metal ion binding, ring finger protein 130 |
| Identity: |
18280 |
| Gene: |
RNF130 |
More about : RNF130 |
| Long gene name: |
ring finger protein 130 |
| Locus: |
5q35, 3 |
| Discovery year: |
2003-05-21 |
| GenBank acession: |
AF155650 |
| Entrez gene record: |
55819 |
| Pubmed identfication: |
10806348 |
| RefSeq identity: |
NM_018434 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000130909 |