| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SERPINB11 |
| Specificity: |
This antibody reacts specifically with SERPINB11 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SERPINB11 |
| Gene ID: |
89778 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Like other members of the serpin family, Niemann-Pick disease, SerpinB11 (serpin peptidase inhibitor, SerpinB11 has been identified as a noninhibitory intracellular protein, Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease, The gene encoding SerpinB11 maps to human chromosome 18, There are a variety of diseases associated with defects in chromosome 18-localized genes, also known as EPIPIN or SERPIN11, clade B (ovalbumin), complement activation, erythropoietic protoporphyria and follicular lymphomas, hereditary hemorrhagic telangiectasia, including the control of blood coagulation, is a 392 amino acid cytoplasmic protein that belongs to the Ov-serpin subfamily and serpin family, member 11), programmed cell death and development, some of which include Trisomy 18 (also known as Edwards syndrome), which houses over 300 protein-coding genes and contains nearly 76 million bases, The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
EPIPIN |
| Also known as: |
SERPINB11 Polyclonal Antibody |
| Other name: |
Anti-SERPINB11 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SERPINB11 |
| Short name: |
Anti-SERPINB11 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SERPINB11 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14221 |
| Gene: |
SERPINB11 |
More about : SERPINB11 |
| Long gene name: |
serpin family B member 11 (gene/pseudogene) |
| Synonyms gene name: |
clade B (ovalbumin), clade B (ovalbumin), clade B (ovalbumin), member 11 (gene/pseudogene) , member 11 serpin peptidase inhibitor, member 11 serpin peptidase inhibitor, serine (or cysteine) proteinase inhibitor |
| Locus: |
18q21, 33 |
| Discovery year: |
2001-06-27 |
| Entrez gene record: |
89778 |
| Pubmed identfication: |
17562709 24172014 |
| RefSeq identity: |
NM_080475 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000060404 |