| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CSPP1 |
| Specificity: |
This antibody reacts specifically with CSPP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CSPP1 |
| Gene ID: |
79848 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Centrosomes act as microtubule organizing centers, Defects in centrosome duplication or function are linked to many human diseases, Duplication of centrosomes occurs once during each cell cycle and requires proper mitotic spindle formation and chromosome segregation, Isoform 1 expression increases throughout the cell cycle and peaks in G2/M phase, The centrosome and spindle pole-associated protein 1 (CSPP1) interacts with centrosomes and microtubules and may play a role in the regulation of G(1)/S-phase progression and spindle assembly, Two isoforms of CSPP1 exist as a result of alternative splicing events, and provide a site for concerted regulation of cell cycle progression, including various forms of cancer, whereas isoform 2 expression is highest in G1 phase and decreases thereafter, Centrosomes are dynamic organelles involved in many aspects of cell function and growth |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ22490 CSPP JBTS21 |
| Also known as: |
CSPP1 Polyclonal Antibody |
| Other name: |
Anti-CSPP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CSPP1 |
| Short name: |
Anti-CSPP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CSPP1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
26193 |
| Gene: |
CSPP1 |
More about : CSPP1 |
| Long gene name: |
centrosome and spindle pole associated protein 1 |
| Locus: |
8q13, 1-q13, 2 |
| Discovery year: |
2005-09-06 |
| GenBank acession: |
AJ583433 |
| Entrez gene record: |
79848 |
| Pubmed identfication: |
15580290 24360807 |
| RefSeq identity: |
NM_024790 |
| Havana BLAST/BLAT: |
OTTHUMG00000164564 |