| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MLF1 |
| Specificity: |
This antibody reacts specifically with MLF1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MLF1/2/3 |
| Gene ID: |
4291 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus, Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels, Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest, Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
MLF1 Polyclonal Antibody |
| Other name: |
Anti-MLF1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MLF1 |
| Short name: |
Anti-MLF1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-myeloid leukemia factor 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0019904 and protein domain specific binding and molecular function, MLF1 and IDBG-63091 and ENSG00000178053 and 4291, MLF1 and IDBG-637188 and ENSBTAG00000004126 and 533379, Mlf1 and IDBG-150128 and ENSMUSG00000048416 and 17349, nuclei, protein domain specific binding, this GO :0002318 and myeloid progenitor cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0005515 : protein binding and also this GO :0019904 : protein domain specific binding, this GO :0005515 : protein binding, this GO :0019904 : protein domain specific binding, myeloid leukemia factor 1 |
| Identity: |
7125 |
| Gene: |
MLF1 |
More about : MLF1 |
| Long gene name: |
myeloid leukemia factor 1 |
| Synonyms name: |
myeloid leukemia factor 1 variant 1 myeloid leukemia factor 1 variant 2 myeloid leukemia factor 1 variant 3 |
| Locus: |
3q25, 32 |
| Discovery year: |
1994-08-29 |
| GenBank acession: |
L49054 |
| Entrez gene record: |
4291 |
| Pubmed identfication: |
8570204 |
| RefSeq identity: |
NM_022443 |
| Havana BLAST/BLAT: |
OTTHUMG00000158775 |