| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TRIM50 |
| Specificity: |
This antibody reacts specifically with TRIM50 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TRIM50 |
| Gene ID: |
135892 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Citrullinemia and Shwachman-Diamond syndrome, Containing one RING-type zinc finger, Lissencephaly, Pendred syndrome, TRIM50 (tripartite motif containing 50), TRIM50 belongs to the TRIM/RBCC family and undergoes post-translational auto-ubiquitination, TRIM50 exists as two alternatively spliced isoforms, The gene encoding TRIM50 maps to human chromosome 7, a B-box type zinc finger, a B30, also known as TRIM50A or E3 ubiquitin-protein ligase TRIM50, and has the ability to form dimers and trimers, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, designated TRIM50 alpha and TRIM50 beta, is a 487 amino acid cytoplasmic protein that functions as an E3 ubiquitin-protein ligase, one RING finger and three zinc-binding domains, which houses over 1, 000 genes, 2/SPRY domain and a single B box-type zinc finger, The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ32804 |
| Also known as: |
TRIM50 Polyclonal Antibody |
| Other name: |
Anti-TRIM50 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TRIM50 |
| Short name: |
Anti-TRIM50 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TRIM50 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19017 |
| Gene: |
TRIM50 |
More about : TRIM50 |
| Long gene name: |
tripartite motif containing 50 |
| Synonyms gene: |
TRIM50A |
| Synonyms gene name: |
tripartite motif-containing 50A tripartite motif-containing 50 |
| Locus: |
7q11, 23 |
| Discovery year: |
2002-08-29 |
| GenBank acession: |
AY081948 |
| Entrez gene record: |
135892 |
| RefSeq identity: |
NM_178125 |
| Classification: |
Tripartite motif containing Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000156805 |