| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ASMTL |
| Specificity: |
This antibody reacts specifically with ASMTL |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ASMTL |
| Gene ID: |
8623 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ASMTL, ASMTL (N-acetylserotonin O-methyltransferase-like protein) is a 621 amino acid protein with a putative catalytic S-adenosyl-L-methionine domain that shares high genetic homology to ASMT, In the pineal gland, Low expression levels are found in spleen, The ASMTL protein is encoded by a gene from the PAR1 region of the X and Y chromosomes, a monoamine neurotransmitter associated with neuronal modulation of emotions, fibroblast, is abundant in pancreas, is synthesized by serotonergic neurons of the central nervous system through metabolism of the essential amino acid L-tryptophan, ovary and colon, placenta, prostate, serotonin can be transformed into the circadian regulatory hormone melatonin by ASMT (acetylserotonin O-methyltransferase) which catalyzes the final reaction in the synthesis pathway, small intestine and leukocytes, testis, thymus, which is considered to be a fusion product of two evolutionarily disparate genes, with potential cytoplasmic localization, Serotonin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ASMTL Polyclonal Antibody |
| Other name: |
Anti-ASMTL Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ASMTL |
| Short name: |
Anti-ASMTL (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ASMTL (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
751 |
| Gene: |
ASMTL |
More about : ASMTL |
| Long gene name: |
acetylserotonin O-methyltransferase-like |
| Locus: |
Xp22, 3 , 3 and Yp11 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
Y15521 |
| Entrez gene record: |
8623 |
| Pubmed identfication: |
9736779 |
| RefSeq identity: |
NM_004192 |
| Classification: |
Pseudoautosomal region 1 |
| Havana BLAST/BLAT: |
OTTHUMG00000021057 |
| Locus Specific Databases: |
Mental Retardation database |