| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ASB13 |
| Specificity: |
This antibody reacts specifically with ASB13 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ASB13 |
| Gene ID: |
79754 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ASB-13 (ankyrin repeat and SOCS box-containing 13) is a 278 amino acid member of the ASB family that contains one SOCS box domain and six ANK repeats, ASB-13 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, Existing as multiple isoforms, Several other families of proteins also contain SOCS boxes, The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex, working in conjunction with other proteins, Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ13134 MGC19879 |
| Also known as: |
ASB13 Polyclonal Antibody |
| Other name: |
Anti-ASB13 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ASB13 |
| Short name: |
Anti-ASB13 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ASB13 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19765 |
| Gene: |
ASB13 |
More about : ASB13 |
| Long gene name: |
ankyrin repeat and SOCS box containing 13 |
| Synonyms gene name: |
ankyrin repeat and SOCS box-containing 13 |
| Locus: |
10p15, 1 |
| Discovery year: |
2002-12-03 |
| GenBank acession: |
AK091935 |
| Entrez gene record: |
79754 |
| Pubmed identfication: |
12076535 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000017603 |