| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FAM135B |
| Specificity: |
This antibody reacts specifically with FAM135B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Intracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FAM135B |
| Gene ID: |
51059 |
| Swiss Prot: |
Q49AJ0 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Chromosome 8 is also associated with Pfeiffer syndrome, Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder, The FAM135B gene product has been provisionally designated FAM135B pending further characterization, Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, Trisomy 8, WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome, also known as Warkany syndrome 2, and certain facial and developmental defects, and typically associated with a poor prognosis, chromosome 8 encodes about 800 genes, congenital hypothyroidism and Waardenburg syndrome, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, Made up of nearly 146 million bases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
C8ORFK32 |
| Also known as: |
FAM135B Polyclonal Antibody |
| Other name: |
Anti-FAM135B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FAM135B |
| Short name: |
Anti-FAM135B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FAM135B (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
28029 |
| Gene: |
FAM135B |
More about : FAM135B |
| Long gene name: |
family with sequence similarity 135 member B |
| Synonyms gene name: |
family with sequence similarity 135, member B |
| Locus: |
8q24, 23 |
| Discovery year: |
2007-05-11 |
| GenBank acession: |
AB196635 |
| Entrez gene record: |
51059 |
| Pubmed identfication: |
8619474 9110174 |
| RefSeq identity: |
NM_015912 |
| Havana BLAST/BLAT: |
OTTHUMG00000149864 |