| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ANKRD6 |
| Specificity: |
This antibody reacts specifically with ANKRD6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ANKRD6/Diversin |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Diversin can directly interact with Dvl (dishevelled), Diversin contains a C-terminal domain that binds Axin/Conductin and a casein kinase-binding domain in its central region that specifically binds casein kinase IÃ, Diversin is believed to play a role in brain development, Diversin may also facilitate canonical Wnt signaling, Due to alternative splicing events, Expressed in a developmentally-regulated manner and at highest levels in the brain, In addition, Members of the ankyrin repeat domain family facilitate protein-protein interactions and function as adaptors of signaling pathways, Through the action of these additional domains, Via its ankyrin repeats, also known as ANKRD6 (ankyrin repeat domain 6), an interaction that is essential for the activation of noncanonical Wnt signaling, is a 727 amino acid protein that contains eight ankyrin repeats and belongs to the ankyrin repeat domain protein family, three Diversin isoforms exist, ©, Diversin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0957 |
| Also known as: |
ANKRD6 Polyclonal Antibody |
| Other name: |
Anti-ANKRD6 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ANKRD6 |
| Short name: |
Anti-ANKRD6 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ANKRD6 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17280 |
| Gene: |
ANKRD6 |
More about : ANKRD6 |
| Long gene name: |
ankyrin repeat domain 6 |
| Synonyms name: |
diversin diego homolog (Drosophila) |
| Locus: |
6q15 |
| Discovery year: |
2001-12-13 |
| GenBank acession: |
AB023174 |
| Entrez gene record: |
22881 |
| Pubmed identfication: |
25218921 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015202 |