| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BRMS1 |
| Specificity: |
This antibody reacts specifically with BRMS1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BRMS1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BRMS1 is stabilized by Hsp90 and may inhibit NF-â, BRMS1 mRNA is expressed in various tissues, BRMS1 may participate in transcriptional regulation by binding to the mSin3/histone deacetylase complex, BRMS1 suppresses metastasis without inhibiting tumorigenicity by modifying several metastasis-associated phenotypes, The expression of BRMS1 in certain cells increases connexin Cx43 expression and reduces connexin Cx32 expression, This produces a gap junction that increases intercellular communication, and colon, and murine mammary, bladder, but the protein is primarily detected in term placenta, including ovary, lung, prostate, similar to those found in normal breast tissue, testis, &hellip, ¹, B activity, Breast cancer metastasis-suppressor 1 (BRMS1) is 246 amino acid protein that acts as a mediator of metastasis suppression in several types of cancer including ovarian |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DKFZP564A063 |
| Also known as: |
BRMS1 Polyclonal Antibody |
| Other name: |
Anti-BRMS1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BRMS1 |
| Short name: |
Anti-BRMS1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-BRMS1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17262 |
| Gene: |
BRMS1 |
More about : BRMS1 |
| Long gene name: |
breast cancer metastasis suppressor 1 |
| Locus: |
11q13, 2 |
| Discovery year: |
2003-12-02 |
| GenBank acession: |
AF147350 |
| Entrez gene record: |
25855 |
| Pubmed identfication: |
10850410 |
| RefSeq identity: |
NM_015399 |
| Havana BLAST/BLAT: |
OTTHUMG00000167081 |