| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Spermine synthase |
| Specificity: |
This antibody reacts specifically with Spermine synthase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Spermine synthase |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Because absence of spermine increases sensitivity of cells to anti-tumor agents, Spermine, a polyamine ubiquitously present in most organisms, is essential for normal cell growth and differentiation, spermine synthase (and other polyamine biosynthesis) is an attractive target for anti-neoplastic therapy, Spermine synthase catalyzes the production of spermine from spermidine |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SPMSY SpS MRSR |
| Also known as: |
Spermine synthase Polyclonal Antibody |
| Other name: |
Anti-Spermine synthase Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Spermine synthase |
| Short name: |
Anti-Spermine synthase (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Spermine synthase (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11123 |
| Gene: |
SMS |
More about : SMS |
| Long gene name: |
spermine synthase |
| Synonyms gene: |
SRS |
| Synonyms gene name: |
Snyder-Robinson X-linked mental retardation syndrome |
| Locus: |
Xp22, 11 |
| Discovery year: |
1997-11-07 |
| GenBank acession: |
AD001528 |
| Entrez gene record: |
6611 |
| Pubmed identfication: |
7546290 9299240 14508504 |
| RefSeq identity: |
NM_004595 |
| Havana BLAST/BLAT: |
OTTHUMG00000021239 |
| Locus Specific Databases: |
Mental Retardation database |