| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GPR120 |
| Specificity: |
This antibody reacts specifically with GPR120 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human G protein coupled receptor 120 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Consequently, FFAs act as signaling molecules and are an important energy source, GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying, GLP-1 belongs to the class of molecules known as the incretins, GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids), One such response occurs when dietary FFAs stimulate GPR120, They also employ various physiological responses through their GPCRs, This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes, which are associated with insulin secreted from the pancreas as a result of food intake, GPR120 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PGR4 |
| Also known as: |
GPR120 Polyclonal Antibody |
| Other name: |
Anti-GPR120 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GPR120 |
| Short name: |
Anti-GPR120 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GPR120 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19061 |
| Gene: |
FFAR4 |
More about : FFAR4 |
| Long gene name: |
free fatty acid receptor 4 |
| Synonyms gene: |
GPR129 GPR120 O3FAR1 |
| Synonyms gene name: |
G protein-coupled receptor 129 G protein-coupled receptor 120 omega-3 fatty acid receptor 1 |
| Locus: |
10q23, 33 |
| Discovery year: |
2003-08-22 |
| Entrez gene record: |
338557 |
| Pubmed identfication: |
20471368 19723586 15619630 20813258 |
| RefSeq identity: |
NM_181745 |
| Classification: |
Free fatty acid receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000034409 |