| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RanBP7 |
| Specificity: |
This antibody reacts specifically with RanBP7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RanBP7/Importin 7 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acting autonomously, At the nucleoplasmic side of the NPC, Importin-7 belongs to the importin b family and contains one importin N-terminal domain, Importin-7 functions in nuclear protein import, Importin-7 is a nuclear protein that is expressed in most tissues, Importin-7 is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran binds to Importin-7, Ran-dependent mechanism, either by acting as an autonomous nuclear transport receptor or as an adapter-like protein in association with the Importin b subunit KPNB1, the Importin-7/substrate complex dissociates and Importin-7 is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran, 038 amino acid protein encoded by the human gene IPO7, Importin 7 is a 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Imp7 |
| Also known as: |
RanBP7 Polyclonal Antibody |
| Other name: |
Anti-RanBP7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RanBP7 |
| Short name: |
Anti-RanBP7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RanBP7 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9852 |
| Gene: |
IPO7 |
More about : IPO7 |
| Long gene name: |
importin 7 |
| Synonyms gene: |
RANBP7 |
| Synonyms gene name: |
RAN binding protein 7 |
| Locus: |
11p15, 4 |
| Discovery year: |
1998-11-30 |
| GenBank acession: |
AF098799 |
| Entrez gene record: |
10527 |
| Pubmed identfication: |
9214382 |
| RefSeq identity: |
NM_006391 |
| Classification: |
Importins |
| Havana BLAST/BLAT: |
OTTHUMG00000165753 |