| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
APLP2 |
| Specificity: |
This antibody reacts specifically with APLP2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human APLP2 |
| Gene ID: |
334 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Inhibits trypsin, May bind to the DNA 5'-GTCACATG-3'(CDEI box), May interact with cellular G-protein signaling pathways, The gene which encodes APLP2 maps to human chromosome 11q24, The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle, The soluble form may have inhibitory properties towards coagulation factors, chymotrypsin, factor XIA and plasma and glandular kallikrein, plasmin, APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients, May play a role in the regulation of hemostasis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
APPH |
| Also known as: |
APLP2 Polyclonal Antibody |
| Other name: |
Anti-APLP2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
APLP2 |
| Short name: |
Anti-APLP2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-APLP2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
598 |
| Gene: |
APLP2 |
More about : APLP2 |
| Long gene name: |
amyloid beta precursor like protein 2 |
| Synonyms gene: |
APPL2 |
| Synonyms gene name: |
amyloid beta (A4) precursor-like protein 2 |
| Locus: |
11q24, 3 |
| Discovery year: |
1993-06-23 |
| GenBank acession: |
L19597 |
| Entrez gene record: |
334 |
| Pubmed identfication: |
10702673 |
| RefSeq identity: |
NM_001642 |
| Havana BLAST/BLAT: |
OTTHUMG00000165767 |