| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GLB1L3 |
| Specificity: |
This antibody reacts specifically with GLB1L3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GLB1L3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Atm mutation leads to the disorder known as ataxia-telangiectasia, GLB1L3 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, With approximately 135 million base pairs and 1, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, 400 genes, GLB1L3 is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ90231 |
| Also known as: |
GLB1L3 Polyclonal Antibody |
| Other name: |
Anti-GLB1L3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GLB1L3 |
| Short name: |
Anti-GLB1L3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GLB1L3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
25147 |
| Gene: |
GLB1L3 |
More about : GLB1L3 |
| Long gene name: |
galactosidase beta 1 like 3 |
| Synonyms gene name: |
beta 1-like 3 galactosidase beta 1-like 3 , galactosidase |
| Locus: |
11q25 |
| Discovery year: |
2006-07-04 |
| Entrez gene record: |
112937 |
| Pubmed identfication: |
12477932 |
| RefSeq identity: |
NM_138416 |
| Havana BLAST/BLAT: |
OTTHUMG00000133524 |