| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Ube2G2 |
| Specificity: |
This antibody reacts specifically with Ube2G2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Ube2G2/UBC7 |
| Gene ID: |
7327 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Expressed throughout the body, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), Two isoforms of UBE2G2 exist due to alternative splicing events, UBE2G2 is an E2 ubiquitin-conjugating enzyme that acts to catalyze the covalent attachment of ubiquitins to various proteins, UBE2G2 shares 100% sequence identity with its mouse counterpart and is thought to be involved in endoplasmic reticulum-associated degradation (ERAD), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction, also known as UBC7, is a 165 amino acid protein involved in ubiquitin-mediated protein degradation, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), UBE2G2 (Ubiquitin-conjugating enzyme E2 G2) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
UBC7 |
| Also known as: |
Ube2G2 Polyclonal Antibody |
| Other name: |
Anti-Ube2G2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Ube2G2 |
| Short name: |
Anti-Ube2G2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Ube2G2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12483 |
| Gene: |
UBE2G2 |
More about : UBE2G2 |
| Long gene name: |
ubiquitin conjugating enzyme E2 G2 |
| Synonyms gene name: |
ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7) ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) ubiquitin-conjugating enzyme E2G 2 |
| Locus: |
21q22, 3 |
| Discovery year: |
1997-11-20 |
| GenBank acession: |
BC008351 |
| Entrez gene record: |
7327 |
| Pubmed identfication: |
9693041 9925943 |
| RefSeq identity: |
NM_182688 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000089179 |