| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CPXM |
| Specificity: |
This antibody reacts specifically with CPXM |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CPXM |
| Gene ID: |
56265 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Belonging to the N/E subfamily, CPXM (metallocarboxypeptidase CPX-1) is a 734 amino acid protein that contains a F5/8 type C domain and likely binds one zinc ion per subunit, CPXM is a unique member of this subfamily in that it does not appear to exhibit any enzymatic activity due to lack of several active-site residues that are present in the catalytic domain of other members of the N/E subfamily, However, It may be involved in cell-cell interactions, Most members of the N/E subfamily contain several domains, Studies showing that CPXM expression is regulated during osteoclastogenesis suggest that CPXM may play a role in osteoclast differentiation, There are two isoforms of CPXM which are a result of alternative splicing events, and are thought to function mostly in protein-protein interactions and/or protein-membrane interactions, function and amino acid sequence similarity, including an active carboxypeptidase domain and signal peptide, member 1) belongs to the peptidase M14 family, no carboxypeptidase activity has yet been detected, thereby targeting the protein to specific locations within the secretory pathway, CPXM (carboxypeptidase X, Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CPX-1 CPX1 |
| Also known as: |
CPXM Polyclonal Antibody |
| Other name: |
Anti-CPXM Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CPXM |
| Short name: |
Anti-CPXM (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CPXM (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
15771 |
| Gene: |
CPXM1 |
More about : CPXM1 |
| Long gene name: |
M14 family member 1 , carboxypeptidase X |
| Synonyms gene: |
CPXM |
| Synonyms gene name: |
carboxypeptidase X (M14 family), member 1 |
| Synonyms name: |
carboxypeptidase-like protein X1 |
| Locus: |
20p13 |
| Discovery year: |
2001-09-17 |
| GenBank acession: |
AL035460 |
| Entrez gene record: |
56265 |
| Pubmed identfication: |
14702039 26603934 |
| RefSeq identity: |
NM_019609 |
| Classification: |
Carboxypeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000031706 |