| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PANK1 |
| Specificity: |
This antibody reacts specifically with PANK1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PANK1 |
| Gene ID: |
53354 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Four known isoforms of PANK1 exist as a result of alternative splicing events, Isoform PANK1a is most highly expressed in brain, Isoform PANK1b is detected at much lower levels in kidney, Localized to the cytoplasm, Of these isoforms, PANK1 is strongly inhibited by acetyl-CoA and manyl-CoA, PANK1a and PANK1b have been identified as the catalytically active isoforms, Pantothenate kinase 1 (PANK1) is a 598 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration, as well as by high concentration of non-esterified CoA (CoASH), brain and testis and is not detected in heart or skeletal muscle, heart, kidney, liver, liver, skeletal muscle and kidney, The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGC24596 PANK1a PANK1b |
| Also known as: |
PANK1 Polyclonal Antibody |
| Other name: |
Anti-PANK1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PANK1 |
| Short name: |
Anti-PANK1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PANK1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8598 |
| Gene: |
PANK1 |
More about : PANK1 |
| Long gene name: |
pantothenate kinase 1 |
| Synonyms gene: |
PANK |
| Synonyms gene name: |
pantothenate kinase |
| Locus: |
10q23, 31 |
| Discovery year: |
2000-05-02 |
| GenBank acession: |
AF355198 |
| Entrez gene record: |
53354 |
| Pubmed identfication: |
11809413 |
| Havana BLAST/BLAT: |
OTTHUMG00000018718 |