| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GIMAP5 |
| Specificity: |
This antibody reacts specifically with GIMAP5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GIMAP5 |
| Gene ID: |
55340 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A member of the GTP-binding superfamily and the immuno-associated nucleotide (IAN) subfamily, Defects in the GIMAP5 gene are associated with systemic lupus erythematosus, GIMAP5 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 7q36, GIMAP5 is highly expressed in CD4 and CD8-positive T-cells and monocytes, GIMAP5 plays a role in T-cell survival and mitochondrial integrity, HIMAP3 or IROD, IAN4, IAN4L1 (immunity-associated nucleotide 4-like 1 protein), IMAP3, also known as IAN5, as well as B-lymphocyte-derived neoplasms, is a 307 amino acid single-pass type IV membrane protein of the mitochondrial outer membrane, 1, GIMAP5 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HIMAP3 IAN5 |
| Also known as: |
GIMAP5 Polyclonal Antibody |
| Other name: |
Anti-GIMAP5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GIMAP5 |
| Short name: |
Anti-GIMAP5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, IMAP family member 5 (polyclonal), antibody to-GTPase |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
GIMAP5 and IDBG-48120 and ENSG00000196329 and 100527949, GTP binding, IMAP family member 5, Plasma membranes, this GO :0005525 and GTP binding and molecular function this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005764 and lysosome and cellular component this GO :0016021 and integral component of membrane and cellular component, this GO :0005525 : GTP binding, this GO :0005525 : GTP binding, 55340, GTPase |
| Identity: |
18005 |
| Gene: |
GIMAP5 |
More about : GIMAP5 |
| Long gene name: |
GTPase, IMAP family member 5 |
| Synonyms gene: |
IAN4L1 |
| Synonyms gene name: |
immune associated nucleotide 4 like 1 (mouse) |
| Synonyms name: |
immune-associated nucleotide-binding protein 5 |
| Locus: |
7q36, 1 |
| Discovery year: |
2002-01-16 |
| GenBank acession: |
AK002158 |
| Entrez gene record: |
55340 |
| RefSeq identity: |
NM_018384 |
| Classification: |
GTPases, IMAP |
| Havana BLAST/BLAT: |
OTTHUMG00000157542 |