| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CUEDC1 |
| Specificity: |
This antibody reacts specifically with CUEDC1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CUEDC1 |
| Gene ID: |
404093 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CUE domains can bind monoubiquitin and may be required for ubiquitination of the proteins in which they are found, CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, Present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways, Two isoforms of CUEDC1 exist due to alternative splicing events, implicating CUEDC1 as a potential tumor marker, suggesting a possible role in protein trafficking and degradation pathways, The coupling of ubiquitin conjugation to endoplasmic reticulum (ER) degradation (CUE) domain functions as a ubiquitin (UB) binding domain that is approximately 40 amino acids in length |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
CUEDC1 Polyclonal Antibody |
| Other name: |
Anti-CUEDC1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CUEDC1 |
| Short name: |
Anti-CUEDC1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CUEDC1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
31350 |
| Gene: |
CUEDC1 |
More about : CUEDC1 |
| Long gene name: |
CUE domain containing 1 |
| Locus: |
17q22 |
| Discovery year: |
2004-03-04 |
| GenBank acession: |
AK000746 |
| Entrez gene record: |
404093 |
| RefSeq identity: |
NM_017949 |
| Havana BLAST/BLAT: |
OTTHUMG00000178775 |