| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IKAROS |
| Specificity: |
This antibody reacts specifically with IKAROS |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IKAROS |
| Gene ID: |
10320 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
B- and T-cells, Binds and activates the enhancer (delta-A element) of the CD3-delta gene, Binds gamma-satellite DNA, Binds with higher affinity to gamma satellite A, Confers early temporal competence to retinal progenitor cells (RPCs), Increases normal apoptosis in adult erythroid cells, Lower expression in bone marrow and small intestine, NuRD and BAF (SWI/SNF), Plays a role in the development of lymphocytes, Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes, Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation, Targets the 2 chromatin-remodeling complexes, in a single complex (PYR complex), spleen and peripheral blood Leukocytes and lymph nodes, to the beta-globin locus in adult erythrocytes, Tissue specificity:Abundantly expressed in thymus, Transcription regulator of hematopoietic cell differentiation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
hIk-1 LyF-1 Hs, 54452 IKAROS PPP1R92 |
| Also known as: |
IKAROS Polyclonal Antibody |
| Other name: |
Anti-IKAROS Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IKAROS |
| Short name: |
Anti-IKAROS (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-IKAROS (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13176 |
| Gene: |
IKZF1 |
More about : IKZF1 |
| Long gene name: |
IKAROS family zinc finger 1 |
| Synonyms gene: |
ZNFN1A1 |
| Synonyms gene name: |
1 (Ikaros) IKAROS family zinc finger 1 (Ikaros) , subfamily 1A, zinc finger protein |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 92 |
| Locus: |
7p12, 2 |
| Discovery year: |
1999-08-23 |
| GenBank acession: |
U40462 |
| Entrez gene record: |
10320 |
| Pubmed identfication: |
1439790 7935426 |
| RefSeq identity: |
NM_006060 |
| Classification: |
Protein phosphatase 1 regulatory subunits Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000155907 |