| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
VRK1 |
| Specificity: |
This antibody reacts specifically with VRK1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human VRK1 |
| Gene ID: |
7443 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, This gene, This gene is widely expressed in human tissues and has increased expression in actively dividing cells, This protein also phosphorylates histone, and carcinomas, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN, casein, fetal liver, in vitro, may regulate cell proliferation, such as those in testis, therefore, thymus, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination, This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
VRK1 Polyclonal Antibody |
| Other name: |
Anti-VRK1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
VRK1 |
| Short name: |
Anti-VRK1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-VRK1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12718 |
| Gene: |
VRK1 |
More about : VRK1 |
| Long gene name: |
vaccinia related kinase 1 |
| Locus: |
14q32, 2 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
AB000449 |
| Entrez gene record: |
7443 |
| Pubmed identfication: |
9344656 |
| RefSeq identity: |
NM_003384 |
| Havana BLAST/BLAT: |
OTTHUMG00000171459 |