| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TNFAIP3 interacting protein 3 |
| Specificity: |
This antibody reacts specifically with TNFAIP3 interacting protein 3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3 |
| Gene ID: |
7128 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ABIN-3 can bind to A20 and inhibit NF-kappaB activation, In contrast, Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3, ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
A20 OTUD7C |
| Also known as: |
TNFAIP3 interacting protein 3 Antibody |
| Other name: |
Anti-TNFAIP3 interacting protein 3 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TNFAIP3 interacting protein 3 |
| Short name: |
Fluor 594, Anti-TNFAIP3 interacting protein 3 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, a-induced protein 3 interacting protein 3, antibody to-tumor necrosis factor |
| Alternative to gene target: |
A20 and OTUD7C and TNFA1P2, TNFAIP3 and IDBG-633691 and ENSBTAG00000000436 and 508105, TNFAIP3 and IDBG-97033 and ENSG00000118503 and 7128, Tnfaip3 and IDBG-135792 and ENSMUSG00000019850 and 21929, alpha-induced protein 3, leucine rich repeat containing receptor signaling pathway and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043621 and protein self-association and molecular function this GO :0045087 and innate immune response and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045779 and negative regulation of bone resorption and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0050691 and regulation of defense response to virus by host and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050869 and negative regulation of B cell activation and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0060548 and negative regulation of cell death and biological process this GO :0061043 and regulation of vascular wound healing and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070429 and negative regulation of nucleotide-binding oli this GO merization domain containing 1 signaling pathway and biological process this GO :0070433 and negative regulation of nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process this GO :0070536 and protein K63-linked deubiquitination and biological process this GO :0070936 and protein K48-linked ubiquitination and biological process this GO :0071108 and protein K48-linked deubiquitination and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0072573 and tolerance induction to lipopolysaccharide and biological process this GO :0090291 and negative regulation of osteoclast proliferation and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000347 and positive regulation of hepatocyte proliferation and biological process this GO :2000349 and negative regulation of CD40 signaling pathway and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, nuclei, protein self-association, this GO :0001922 and B-1 B cell homeostasis and biological process this GO :0002020 and protease binding and molecular function this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002634 and regulation of germinal center formation and biological process this GO :0002677 and negative regulation of chronic inflammatory response and biological process this GO :0003677 and DNA binding and molecular function this GO :0004221 and ubiquitin thiolesterase activity and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004843 and ubiquitin-specific protease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016579 and protein deubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0019900 and kinase binding and molecular function this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032691 and negative regulation of interleukin-1 beta production and biological process this GO :0032703 and negative regulation of interleukin-2 production and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0034136 and negative regulation of toll-like receptor 2 signaling pathway and biological process this GO :0034140 and negative regulation of toll-like receptor 3 signaling pathway and biological process this GO :0034144 and negative regulation of toll-like receptor 4 signaling pathway and biological process this GO :0034148 and negative regulation of toll-like receptor 5 signaling pathway and biological process this GO :0035871 and protein K11-linked deubiquitination and biological process this GO :0035872 and nucleotide-binding domain, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0003677 : DNA binding and also this GO :0004221 : ubiquitin thiolesterase activity and also this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0004843 : ubiquitin-specific protease activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0019900 : kinase binding and also this GO :0043130 : ubiquitin binding and also this GO :0043621 : protein self-association, this GO :0003677 : DNA binding, this GO :0004221 : ubiquitin thiolesterase activity, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004843 : ubiquitin-specific protease activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0019900 : kinase binding, this GO :0043130 : ubiquitin binding, this GO :0043621 : protein self-association, tumor necrosis factor |
| Identity: |
11896 |
| Gene: |
TNFAIP3 |
More about : TNFAIP3 |
| Long gene name: |
TNF alpha induced protein 3 |
| Synonyms gene name: |
alpha-induced protein 3 , tumor necrosis factor |
| Locus: |
6q23, 3 |
| Discovery year: |
1992-10-20 |
| GenBank acession: |
M59465 |
| Entrez gene record: |
7128 |
| Pubmed identfication: |
2118515 |
| Classification: |
OTU domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015664 |