| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SEMA4A |
| Specificity: |
This antibody reacts specifically with SEMA4A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SEMA4A |
| Gene ID: |
64218 |
| Swiss Prot: |
Q9H3S1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Inhibits angiogenesis, Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity), PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling, Plays a role in priming antigen-specific T-cells, Promotes axon growth cone collapse, Promotes phosphorylation of TIMD2, and thereby contributes to adaptive immunity, promotes differentiation of Th1 T-helper cells, Cell surface receptor for PLXNB1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SemB FLJ12287 CORD10 |
| Also known as: |
SEMA4A Polyclonal Antibody |
| Other name: |
Anti-SEMA4A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SEMA4A |
| Short name: |
Anti-SEMA4A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
(semaphorin) 4A (polyclonal), ALEXA Fluor 594, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, antibody to-sema domain |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
(semaphorin) 4A, Plasma membranes, SEMA4A and IDBG-103399 and ENSG00000196189 and 64218, SEMA4A and IDBG-631665 and ENSBTAG00000012228 and 510239, Sema4a and IDBG-160873 and ENSMUSG00000028064 and 20351, immunoglobulin domain (Ig), protein binding, this GO :0001525 and angiogenesis and biological process this GO :0002292 and T cell differentiation involved in immune response and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0007409 and axonogenesis and biological process this GO :0007411 and axon guidance and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0010594 and regulation of endothelial cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0045063 and T-helper 1 cell differentiation and biological process this GO :0071526 and semaphorin-plexin signaling pathway and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, transmembrane domain (TM) and short cytoplasmic domain, sema domain |
| Identity: |
10729 |
| Gene: |
SEMA4A |
More about : SEMA4A |
| Long gene name: |
semaphorin 4A |
| Synonyms gene: |
SEMAB |
| Synonyms gene name: |
(semaphorin) 4A , immunoglobulin domain (Ig), sema domain, transmembrane domain (TM) and short cytoplasmic domain |
| Locus: |
1q22 |
| Discovery year: |
2004-04-22 |
| GenBank acession: |
AK022416 |
| Entrez gene record: |
64218 |
| Pubmed identfication: |
7748561 |
| RefSeq identity: |
NM_022367 |
| Classification: |
Semaphorins |
| Havana BLAST/BLAT: |
OTTHUMG00000014042 |