| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
EDA2R |
| Specificity: |
This antibody reacts specifically with EDA2R |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human EDA2R/TNFRSF27 |
| Gene ID: |
60401 |
| Swiss Prot: |
Q9HAV5 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Activation seems to be mediated by binding to TRAF3 and TRAF6, Mediates the activation of the NF-kappa-B and JNK pathways, but not for EDA isoform A1, Receptor for EDA isoform A2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
XEDAR EDA-A2R EDAA2R TNFRSF27 |
| Also known as: |
EDA2R Polyclonal Antibody |
| Other name: |
Anti-EDA2R Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
EDA2R |
| Short name: |
Anti-EDA2R (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ectodysplasin A2 receptor (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
EDA2R and IDBG-636425 and ENSBTAG00000047326 and 100301324, EDA2R and IDBG-73673 and ENSG00000131080 and 60401, Eda2r and IDBG-161374 and ENSMUSG00000034457 and 245527, Plasma membranes, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0005031 and tumor necrosis factor-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0008544 and epidermis development and biological process this GO :0009790 and embryo development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030154 and cell differentiation and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005031 : tumor necrosis factor-activated receptor activity and also this GO :0005515 : protein binding, this GO :0005031 : tumor necrosis factor-activated receptor activity, this GO :0005515 : protein binding, ectodysplasin A2 receptor |
| Identity: |
17756 |
| Gene: |
EDA2R |
More about : EDA2R |
| Long gene name: |
ectodysplasin A2 receptor |
| Locus: |
Xq12 |
| Discovery year: |
2004-08-17 |
| GenBank acession: |
AF298812 |
| Entrez gene record: |
60401 |
| Pubmed identfication: |
11039935 |
| RefSeq identity: |
NM_021783 |
| Classification: |
Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000021736 |
| Locus Specific Databases: |
Mental Retardation database |