| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CARD17 |
| Specificity: |
This antibody reacts specifically with CARD17 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CARD17/INCA |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
However, Inhibits the release of IL1B in response to LPS in monocytes, do not induce NF-kappa-B activation, unlike CASP1, Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
INCA |
| Also known as: |
CARD17 Polyclonal Antibody |
| Other name: |
Anti-CARD17 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CARD17 |
| Short name: |
Anti-CARD17 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 17 (polyclonal), antibody to-caspase recruitment domain family |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CARD17 and IDBG-547134 and ENSG00000255221 and 440068, Cytoplasm, cysteine-type endopeptidase inhibitor activity, member 17, this GO :0004869 and cysteine-type endopeptidase inhibitor activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0042981 and regulation of apoptotic process and biological process, this GO :0004869 : cysteine-type endopeptidase inhibitor activity, this GO :0004869 : cysteine-type endopeptidase inhibitor activity, caspase recruitment domain family |
| Identity: |
33827 |
| Gene: |
CARD17 |
More about : CARD17 |
| Long gene name: |
caspase recruitment domain family member 17 |
| Synonyms gene name: |
caspase recruitment domain family, member 17 |
| Synonyms name: |
Inhibitory CARD |
| Locus: |
11q22, 3 |
| Discovery year: |
2008-10-29 |
| Entrez gene record: |
440068 |
| Pubmed identfication: |
15383541 |
| RefSeq identity: |
NM_001007232 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166163 |