| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CARD15 |
| Specificity: |
This antibody reacts specifically with CARD15 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CARD15 |
| Gene ID: |
64127 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is a form of sarcoidosis manifesting in children younger than 4 years of age, Early-onset sarcoidosis is quite rare and has a distinct triad of skin, Granulomas predominantly invade the lungs and the lymphatic system, Sarcoidosis is an idiopathic, but also skin, early-onset sarcoidosis is progressive and in many cases causes severe complications, eyes and other organs may be involved, inflammatory disease characterized by the formation of immune granulomas in involved organs, joint and eye disorders, joint destruction and visceral involvement, liver, spleen, such as blindness, systemic, without apparent pulmonary involvement, Defects in NOD2 are the cause of sarcoidosis early-onset (EOS) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BLAU CD PSORAS1 CLR16, 3 NLRC2 |
| Also known as: |
CARD15 Polyclonal Antibody |
| Other name: |
Anti-CARD15 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CARD15 |
| Short name: |
Anti-CARD15 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CARD15 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5331 |
| Gene: |
NOD2 |
More about : NOD2 |
| Long gene name: |
nucleotide binding oligomerization domain containing 2 |
| Synonyms gene: |
IBD1 CARD15 |
| Synonyms gene name: |
caspase recruitment domain family, member 15 |
| Synonyms name: |
CARD domain containing 2 , leucine rich repeat and CARD domain containing 2 NOD-like receptor C2 NLR family, nucleotide-binding oligomerization domain |
| Locus: |
16q12, 1 |
| Discovery year: |
1998-07-10 |
| GenBank acession: |
AF178930 |
| Entrez gene record: |
64127 |
| Pubmed identfication: |
7809109 8587604 |
| RefSeq identity: |
NM_022162 |
| Classification: |
Caspase recruitment domain containing NLR family |
| Havana BLAST/BLAT: |
OTTHUMG00000133171 |
| Locus Specific Databases: |
LRG_177 |