| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Thrap3 |
| Specificity: |
This antibody reacts specifically with Thrap3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Thrap3/TRAP150 |
| Gene ID: |
389541 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
TRAP100, TRAP150, TRAP150 and TRAP230 facilitate TR induced transcription by associating with an additional transcriptional coactivating complex SMCC (SRB and MED protein cofactor complex), TRAP220 and TRAP100 are widely expressed and most abundantly detected in skeletal muscle, TRAP220 and TRAP230, TRAP95, The TRAP complex consists of numerous proteins ranging in size including TRAP95, These complexes include the thyroid hormone receptor-associated protein (TRAP) complex, heart and placenta, that are characterized by the presence of a nuclear receptor recognition motif which mediates the ligand-dependent binding of TRAP proteins to the nuclear receptors, transcription is regulated in part by high molecular weight coactivating complexes that mediate signaling between transcriptional activators and initiation factors, vitamin D receptors and other steroid receptors to facilitate hormone induced transcriptional activation, which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, which interacts with thyroid receptors (TR), In mammalian cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TRAP150 |
| Also known as: |
Thrap3 Polyclonal Antibody |
| Other name: |
Anti-Thrap3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Thrap3 |
| Short name: |
Anti-Thrap3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Thrap3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
22964 |
| Gene: |
THRAP3 |
More about : THRAP3 |
| Long gene name: |
thyroid hormone receptor associated protein 3 |
| Locus: |
1p34, 3 |
| Discovery year: |
2004-01-30 |
| GenBank acession: |
AF117756 |
| Entrez gene record: |
9967 |
| RefSeq identity: |
NM_005119 |
| Havana BLAST/BLAT: |
OTTHUMG00000007866 |