| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AKAP5 |
| Specificity: |
This antibody reacts specifically with AKAP5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AKAP5 |
| Gene ID: |
9495 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), Members of this family, Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell, This family of proteins has been designated A-kinase anchoring proteins (AKAP) (1-3), To maintain this specific localization, and the DNA binding AKAP 95, display differential tissue specificity and localization (4-6), including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins, which are a network of proteins located on the internal surfaces of excitatory synapses, The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates (1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AKAP75 AKAP79 |
| Also known as: |
AKAP5 Polyclonal Antibody |
| Other name: |
Anti-AKAP5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AKAP5 |
| Short name: |
Anti-AKAP5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-AKAP5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
375 |
| Gene: |
AKAP5 |
More about : AKAP5 |
| Long gene name: |
A-kinase anchoring protein 5 |
| Synonyms gene name: |
A kinase (PRKA) anchor protein 5 |
| Locus: |
14q23, 3 |
| Discovery year: |
1999-09-16 |
| GenBank acession: |
M90359 |
| Entrez gene record: |
9495 |
| Pubmed identfication: |
1512224 1618839 |
| Classification: |
A-kinase anchoring proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000029634 |