| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PPAPDC3 |
| Specificity: |
This antibody reacts specifically with PPAPDC3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PPAPDC3 |
| Gene ID: |
84814 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Has no detectable enzymatic activity, It is a member of the PAP2 superfamily of phosphatases and haloperoxidases, Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis, PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR, PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues, also known as nuclear envelope transmembrane protein 39 (NET39), in part through effects on MTOR signaling, was initially discovered in an in silico screen for secreted or membrane proteins, PPAPDC3, Plays a role as negative regulator of myoblast differentiation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGC12921 FLJ14662 NET39 |
| Also known as: |
PPAPDC3 Polyclonal Antibody |
| Other name: |
Anti-PPAPDC3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PPAPDC3 |
| Short name: |
Anti-PPAPDC3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PPAPDC3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
28174 |
| Gene: |
PLPP7 |
More about : PLPP7 |
| Long gene name: |
phospholipid phosphatase 7 (inactive) |
| Synonyms gene: |
C9orf67 PPAPDC3 |
| Synonyms gene name: |
chromosome 9 open reading frame 67 phosphatidic acid phosphatase type 2 domain containing 3 |
| Synonyms name: |
nuclear envelope transmembrane protein NET39 |
| Locus: |
9q34, 13 |
| Discovery year: |
2004-01-06 |
| GenBank acession: |
AK027568 |
| Entrez gene record: |
84814 |
| Pubmed identfication: |
12958361 |
| RefSeq identity: |
NM_032728 |
| Classification: |
Phospholipid phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000020822 |