| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HBXIP |
| Specificity: |
This antibody reacts specifically with HBXIP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HBXIP |
| Gene ID: |
10542 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway, HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
XIP MGC71071 |
| Also known as: |
HBXIP Polyclonal Antibody |
| Other name: |
Anti-HBXIP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HBXIP |
| Short name: |
Anti-HBXIP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, MAPK and Mammalian target on rapamycin activator 5 (polyclonal), antibody to-late endosomal/lysosomal adaptor |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cytoplasm, HBXIP and IDBG-100979 and ENSG00000134248 and 10542, HBXIP and IDBG-648604 and ENSBTAG00000045839 and, HBXIP and XIP, Hbxip and IDBG-489097 and ENSMUSG00000087260 and 68576, MAPK and MTOR activator 5, protein complex scaffold, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0008361 and regulation of cell size and biological process this GO :0009615 and response to virus and biological process this GO :0019079 and viral genome replication and biological process this GO :0032008 and positive regulation of TOR signaling and biological process this GO :0032947 and protein complex scaffold and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0061462 and protein localization to lysosome and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0071986 and Ragulator complex and cellular component, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0032947 : protein complex scaffold, this GO :0005515 : protein binding, this GO :0032947 : protein complex scaffold, late endosomal/lysosomal adaptor |
| Identity: |
17955 |
| Gene: |
LAMTOR5 |
More about : LAMTOR5 |
| Long gene name: |
MAPK and MTOR activator 5 , late endosomal/lysosomal adaptor |
| Synonyms gene: |
HBXIP |
| Synonyms gene name: |
hepatitis B virus x interacting protein |
| Synonyms name: |
HBx-interacting protein hepatitis B virus x-interacting protein (9, 6kD) |
| Locus: |
1p13, 3 |
| Discovery year: |
2002-01-10 |
| GenBank acession: |
AF029890 |
| Entrez gene record: |
10542 |
| Pubmed identfication: |
9499022 22980980 |
| RefSeq identity: |
NM_006402 |
| Classification: |
Ragulator complex |
| Havana BLAST/BLAT: |
OTTHUMG00000011568 |