| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MAGEL2 |
| Specificity: |
This antibody reacts specifically with MAGEL2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MAGEL2 |
| Gene ID: |
54551 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Because of their specific expression on tumor cells, Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes, These antigens ought to be strictly tumor specific, Though the function of MAGE is unknown, and, expressed in tumor cells of various histological types, for some of them, may play a role in embryonal development and tumor transformation or aspects of tumor progression, placenta, these antigens are of particular interest for antitumor immunotherapy, with the exception of male germ cells, Melanoma-associated antigen (MAGE) are completely silent in normal tissues |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
nM15 |
| Also known as: |
MAGEL2 Polyclonal Antibody |
| Other name: |
Anti-MAGEL2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MAGEL2 |
| Short name: |
Anti-MAGEL2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MAGEL2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6814 |
| Gene: |
MAGEL2 |
More about : MAGEL2 |
| Long gene name: |
MAGE family member L2 |
| Synonyms gene: |
NDNL1 |
| Synonyms gene name: |
MAGE-like 2 melanoma antigen family L2 |
| Locus: |
15q11, 2 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
AJ243531 |
| Entrez gene record: |
54551 |
| Pubmed identfication: |
10556298 |
| RefSeq identity: |
NM_019066 |
| Classification: |
MAGE family |
| Havana BLAST/BLAT: |
OTTHUMG00000167582 |
| Locus Specific Databases: |
LRG_1046 |