| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MAP3K9+Thr312 |
| Specificity: |
This antibody reacts specifically with MAP3K9 (Thr312) |
| Modification: |
Phosphorylation |
| Modification site: |
Thr312 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human MAP3K9 around the phosphorylation site of Thr312 |
| Gene ID: |
4293 |
| Swiss Prot: |
P80192 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Once activated, Plays also a role in mitochondrial death signaling pathway, Plays an important role in the cascades of cellular responses evoked by changes in the environment, The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs, including the release cytochrome c, leading to apoptosis, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PRKE1 MEKK9 |
| Also known as: |
MAP3K9 (Thr312) Polyclonal Antibody |
| Other name: |
Anti-MAP3K9 (Thr312) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MAP3K9 (Thr312) |
| Short name: |
Anti-MAP3K9 (Thr312) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MAP3K9 (Thr312) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6861 |
| Gene: |
MAP3K9 |
More about : MAP3K9 |
| Long gene name: |
mitogen-activated protein kinase kinase kinase 9 |
| Synonyms gene: |
MLK1 |
| Locus: |
14q24, 2 |
| Discovery year: |
1993-12-15 |
| GenBank acession: |
AF251442 |
| Entrez gene record: |
4293 |
| Classification: |
Mitogen-activated protein kinase kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000171249 |