| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MAPK organizer 1 |
| Specificity: |
This antibody reacts specifically with MAPK organizer 1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MAPK organizer 1 |
| Gene ID: |
84292 |
| Swiss Prot: |
Q9BRX9 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3, At low concentrations it enhances ERK activation, May act by recruiting signaling complexes to a specific upstream activator (By similarity), May also be involved in pre-mRNA splicing, May promote degradation of HIF1A, linking ERK responses to specific agonists, whereas high concentrations lead to the inhibition of ERK activation, Molecular scaffold protein for various multimeric protein complexes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MORG1 |
| Also known as: |
MAPK organizer 1 Polyclonal Antibody |
| Other name: |
Anti-MAPK organizer 1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MAPK organizer 1 |
| Short name: |
Anti-MAPK organizer 1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MAPK organizer 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
32672 |
| Gene: |
WDR83 |
More about : WDR83 |
| Long gene name: |
WD repeat domain 83 |
| Synonyms name: |
MAPK organizer 1 |
| Locus: |
19p13, 13 |
| Discovery year: |
2010-01-25 |
| GenBank acession: |
AK074525 |
| Entrez gene record: |
84292 |
| Pubmed identfication: |
15118098 16407229 |
| RefSeq identity: |
NM_032332 |
| Classification: |
WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000169356 |