| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TLX3 |
| Specificity: |
This antibody reacts specifically with TLX3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TLX3 |
| Gene ID: |
30012 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is overexpressed in childhood acute lumphoblastic leukemia, Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors, This transcription factor is required for hematopoiesis, TLX3 (HOX11L2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RNX |
| Also known as: |
TLX3 Polyclonal Antibody |
| Other name: |
Anti-TLX3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TLX3 |
| Short name: |
Anti-TLX3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-T-cell leukemia homeobox 3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0007417 and central nervous system development and biological process this GO :0007585 and respiratory gaseous exchange and biological process this GO :0030182 and neuron differentiation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0048665 and neuron fate specification and biological process, TLX3 and IDBG-57439 and ENSG00000164438 and 30012, TLX3 and IDBG-628419 and ENSBTAG00000010003 and 618473, Tlx3 and IDBG-161051 and ENSMUSG00000040610 and 27140, nuclei, sequence-specific DNA binding, this GO :0001708 and cell fate specification and biological process this GO :0001764 and neuron migration and biological process this GO :0002087 and regulation of respiratory gaseous exchange by neurological system process and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, 789584, T-cell leukemia homeobox 3 |
| Identity: |
13532 |
| Gene: |
TLX3 |
More about : TLX3 |
| Long gene name: |
T-cell leukemia homeobox 3 |
| Synonyms gene: |
HOX11L2 |
| Synonyms gene name: |
homeo box 11-like 2 T-cell leukemia, homeobox 3 |
| Locus: |
5q35, 1 |
| Discovery year: |
2001-12-17 |
| GenBank acession: |
AJ223798 |
| Entrez gene record: |
30012 |
| Pubmed identfication: |
11435718 11435716 |
| Classification: |
NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000163207 |