| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NET1 |
| Specificity: |
This antibody reacts specifically with NET1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NET1 |
| Gene ID: |
10276 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
7 and 18, Alternative splicing results in multiple transcript variants that encode different protein isoforms, Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP, Pseudogenes of this gene are located on the long arms of chromosomes 1, The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation, This gene is part of the family of Rho guanine nucleotide exchange factors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ARHGEF8 NET1A |
| Also known as: |
NET1 Polyclonal Antibody |
| Other name: |
Anti-NET1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NET1 |
| Short name: |
Anti-NET1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-neuroepithelial cell transforming 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ARHGEF8 and NET1A, GTP-Rho binding, NET1 and IDBG-48898 and ENSG00000173848 and 10276, NET1 and IDBG-639242 and ENSBTAG00000007648 and 507365, Net1 and IDBG-128472 and ENSMUSG00000021215 and 56349, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0017049 and GTP-Rho binding and molecular function this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051451 and myoblast migration and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :1900026 and positive regulation of substrate adhesion-dependent cell spreading and biological process, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0017049 : GTP-Rho binding, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005515 : protein binding, this GO :0017049 : GTP-Rho binding, neuroepithelial cell transforming 1 |
| Identity: |
14592 |
| Gene: |
NET1 |
More about : NET1 |
| Long gene name: |
neuroepithelial cell transforming 1 |
| Locus: |
10p15, 1 |
| Discovery year: |
2001-02-08 |
| GenBank acession: |
AJ010046 |
| Entrez gene record: |
10276 |
| Pubmed identfication: |
8649828 |
| RefSeq identity: |
NM_005863 |
| Classification: |
Rho guanine nucleotide exchange factors Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000017596 |