| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PIGR |
| Specificity: |
This antibody reacts specifically with PIGR |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PIGR |
| Gene ID: |
5284 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene, The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells, the complex is then transported across the cell to be secreted at the apical surface, PIGR is a member of the immunoglobulin superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
PIGR Polyclonal Antibody |
| Other name: |
Anti-PIGR Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PIGR |
| Short name: |
Anti-PIGR (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-polymeric immunoglobulin receptor (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, Extracellular, PIGR and IDBG-106295 and ENSG00000162896 and 5284, Pigr and IDBG-190490 and ENSMUSG00000026417 and 18703, protein binding, this GO :0001580 and detection of chemical stimulus involved in sensory perception of bitter taste and biological process this GO :0001792 and polymeric immunoglobulin receptor activity and molecular function this GO :0001895 and retina homeostasis and biological process this GO :0002415 and immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor and biological process this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0038093 and Fc receptor signaling pathway and biological process this GO :0043113 and receptor clustering and biological process this GO :0043235 and receptor complex and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001792 : polymeric immunoglobulin receptor activity, this GO :0001792 : polymeric immunoglobulin receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 105276 and IDBG-629177 and ENSBTAG00000019798 and 281401, polymeric immunoglobulin receptor |
| Identity: |
8968 |
| Gene: |
PIGR |
More about : PIGR |
| Long gene name: |
polymeric immunoglobulin receptor |
| Locus: |
1q32, 1 |
| Discovery year: |
1989-06-06 |
| Entrez gene record: |
5284 |
| RefSeq identity: |
NM_002644 |
| Classification: |
V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000036581 |