| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Centaurin gamma 1 |
| Specificity: |
This antibody reacts specifically with Centaurin gamma 1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Centaurin gamma 1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity, Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt, It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system, It is overexpressed in cancer cells, It seems to be oncogenic, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase, prevents apoptosis and promotes cancer cell invasion, which also shows strong GTPase activity, GTPase-activating protein (GAP) for ARF1 and ARF5 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AGAP-2, AGAP2_HUMAN, ANK repeat and PH domain-containing protein 2, ANK repeat and PH domain-containing protein 2, ANK repeat and PH domains 2, ANK repeat and PH domains 2, Agap2, Agap2 ArfGAP with GTPase domain, Arf GAP with GTP binding protein like, Arf GAP with GTP-binding protein-like, Arf GAP with GTP-binding protein-like, Arf-GAP with GTPase, Arf-GAP with GTPase, ArfGAP with GTPase domain, Centaurin-gamma-1, Centg1, Cnt-g1, Cnt2, GGAP2, GTP binding and GTPase activating protein 2, GTP-binding and GTPase activating protein 2, GTP-binding and GTPase-activating protein 2, Nuclear GTPase PIKE, PI3K ENHANCER, PIKE, Phosphatidylinositol-3-kinase enhancer, Phosphoinositide 3 kinase enhancer, ankyrin repeat and PH domain 2, ankyrin repeat and PH domain 2, ankyrin repeat and pleckstrin homology domains 2, centaurin gamma1, cnt g1, Centaurin gamma 1 |
| Also known as: |
Centaurin gamma 1 Polyclonal Antibody |
| Other name: |
Anti-Centaurin gamma 1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Centaurin gamma 1 |
| Short name: |
Anti-Centaurin gamma 1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Centaurin g 1 (polyclonal) |
| Alternative technique: |
polyclonals |