| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PRODH |
| Specificity: |
This antibody reacts specifically with PRODH |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Mitochondrion |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PRODH |
| Gene ID: |
5625 |
| Swiss Prot: |
O43272 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defective PRODH may be involved in the psychiatric and behavioral phenotypes associated with the 22q11 velocardiofacial and DiGeorge syndrome and may be associated with susceptibility to schizophrenia 4 (SCZD4), Defects in PRODH are the cause of hyperprolinemia type 1, a disorder characterized by elevated serum proline levels, or P5C during the degradation of the amino acid Proline, Proline oxidase catalyzes the conversion of proline to pyrroline-5-carboxylate |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HSPOX2 PRODH1 PIG6 PRODH2 TP53I6 |
| Also known as: |
PRODH Polyclonal Antibody |
| Other name: |
Anti-PRODH Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PRODH |
| Short name: |
Anti-PRODH (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-proline dehydrogenase (oxidase) 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, Cytoplasm, FAD binding, HSPOX2 and PIG6 and POX and PRODH1 and PRODH2 and TP53I6, PRODH and IDBG-1197 and ENSG00000100033 and 5625, Prodh and IDBG-141018 and ENSMUSG00000003526 and 19125, this GO :0004657 and proline dehydrogenase activity and molecular function this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0006537 and glutamate biosynthetic process and biological process this GO :0006560 and proline metabolic process and biological process this GO :0006562 and proline catabolic process and biological process this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0010133 and proline catabolic process to glutamate and biological process this GO :0019470 and 4-hydroxyproline catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0071949 and FAD binding and molecular function, this GO :0004657 : proline dehydrogenase activity, this GO :0004657 : proline dehydrogenase activity and also this GO :0071949 : FAD binding, this GO :0071949 : FAD binding, 20369 and IDBG-637904 and ENSBTAG00000047676 and 505094, proline dehydrogenase (oxidase) 1 |
| Identity: |
9453 |
| Gene: |
PRODH |
More about : PRODH |
| Long gene name: |
proline dehydrogenase 1 |
| Synonyms gene name: |
proline dehydrogenase (proline oxidase ) |
| Synonyms name: |
proline oxidase |
| Locus: |
22q11, 21 |
| Discovery year: |
1996-12-12 |
| GenBank acession: |
AF010310 |
| Entrez gene record: |
5625 |
| Pubmed identfication: |
9385373 10192398 |
| RefSeq identity: |
NM_016335 |
| Havana BLAST/BLAT: |
OTTHUMG00000150163 |