| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CDO1 |
| Specificity: |
This antibody reacts specifically with CDO1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CDO1 |
| Gene ID: |
1036 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine, CDO1 is involved in pyruvate-, Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, Human CDO1 shares 94% amino acid identity with its rat counterpart, The gene encoding CDO1 maps to human chromosome 5, Via its catalytic activity, hypotaurine from L-cysteine: step 1/2, pancreas and heart, suggesting a conserved role between species, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell, taurine biosynthesis, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis, which contains 181 million base pairs and comprises nearly 6% of the human genome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome, CDO1 (cysteine dioxygenase, PathwayOrganosulfur biosynthesis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
CDO1 Polyclonal Antibody |
| Other name: |
Anti-CDO1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CDO1 |
| Short name: |
Anti-CDO1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CDO1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1795 |
| Gene: |
CDO1 |
More about : CDO1 |
| Long gene name: |
cysteine dioxygenase type 1 |
| Synonyms gene name: |
cysteine dioxygenase, type I |
| Locus: |
5q22, 3 |
| Discovery year: |
1996-09-13 |
| Entrez gene record: |
1036 |
| Pubmed identfication: |
7524679 |
| RefSeq identity: |
NM_001801 |
| Havana BLAST/BLAT: |
OTTHUMG00000128891 |